The cross effects of methadone differ from the amount of the chemical that you take. 60-80 mgs can stop the euphoria that heroine and other opiates give the user while a low dosage can stop the effects a weaker opiates like hydrocodone. This is a nice thought for the people who work with recovering addicts since the worry of them leaving the clinic and doing more opiates.
A large misconception is that methadone can be used to help people get off of cocaine, alcohol, and meth, but this is not true. The fact that methadone can stop the effects of harder and more dangerous opioids is a huge saving grace in my opinion.
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